Background/Aims Long-term usage of aspirin could be a risk factor of peptic ulcer diseases. group and 38 in the placebo group. There is no occurrence of peptic ulcer in both organizations. The occurrence of gastritis was considerably higher in the placebo group (44.4% vs. 10.0%, infection induces chronic swelling from the gastric mucosa, which may be frustrated by long-term usage of ASA. ASA could be a risk element for peptic ulcer in eradication only increases the threat of peptic ulcer a lot more than H. pylori eradication coupled with PPI maintenance in long-term ASA users. Consequently, eradication isn’t currently suggested for long-term ASA users with out a earlier background of peptic ulcer [19,20]. As the position of infection had not been evaluated with this research, the result of Albis in preventing gastric mucosal damage due to ASA cannot be analyzed relating to infection. Even though influence of contamination on our outcomes could not become examined, no ulcers had been developed through the research period in both treatment and placebo organizations. Furthermore, the mucosal damage may not differ per the position of contamination. In earlier studies, the precautionary aftereffect of PPIs on peptic ulcers in long-term ASA users had not been different based on the position of contamination at 12 weeks, but obvious in infection had not been evaluated, that could influence the introduction of ulcers in long-term ASA users. However, this is actually the 1st report around the gastroprotective aftereffect of a combined mix of ranitidine, sucralfate, and bismuth in long-term ASA users. To conclude, Albis avoided gastric mucosal damage in ASA users. Nevertheless, further research are warranted to show the preventive aftereffect of Albis against peptic ulcer in long-term ASA users for over 24 weeks. 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